While study is slightly lacking, trazodone has actually a half-life of around eight come 15 hours. Medicine are greatly out of the mechanism after about four to five half-lives, so that takes roughly 32 to 75 hrs for trazodone to leaving the body.

You are watching: How long does trazodone stay in your system


Trazodone is one antidepressant, sold generally in two forms: trazodone hydrochloride (Desyrel) or trazodone hydrochloride extended-release (Oleptro). That is openly soluble in water and also comes in the type of a tablet.

It is usually prescribed in doses varying from 150 mg every day to 400 mg per day, with doses because that severe cases going as high together 600 mg per day. It must only it is in taken together prescribed.

Get instant Treatment Help.
(844) 899-5777

I would choose to conversation online

How long Trazodone continues to be in the Body

Toxicology study into exactly how long trazodone have the right to be recognize in the human body is relatively scarce, namely due to the fact that it has not been shown to have high abuse potential and is not generally tested because that in program drug tests. Part data points are available; however, the can assist you identify whether it is likely still in your system.

According to the U.S. National Library of Medicine, once taken in an extended-release dental dose, 70 to 75 percent the trazodone is excreted in urine within 72 hours. The dose in question, in this case, to be a single 300 mg dose.

Data top top trazodone’s detectability in blood testing is much more limited. Urine tends to be a much less invasive method for drug detection in general while simultaneously being about as likely, or more, to detect abuse in the exact same window. Precisely how equivalent the window of detection is between blood and also urine because that trazodone is right now unavailable.

Most blood experimentation for trazodone use actually come post-mortem from self-destruction victims. Trazodone have the right to be poisonous if abused, especially if mixed with other drugs, and it can also cause suicidal thoughts.

If you are on trazodone and experience suicidal thoughts, report them to your medical professional immediately.

Rough Estimates

Dr. Jim Phelps, a psychiatrist that specializes in bipolar disorder and also depression, has written top top the subject of antidepressants and also how lengthy they generally stay in the body. While the admits it is a unstable estimate, the discusses how numerous doctors use a few factors to quickly estimate how long drugs stay in the body.

 How long is the drug’s half-life? What is that number multiply by about four or five?

Since trazodone’s half-life is about eight to 15 hours, it have to take somewhere between 32 come 75 hrs for the medicine to be gone from her system.

Of course, the chemistry of one individual’s body is rarely that simple. The following components can affect exactly exactly how long a drug remains in the body:

 Age Weight Sex Overall health Length that time the drug has been taken Amount that drug continuously taken, particularly in situations of abusive doses

Generally speaking, the an ext of a drug you take and the smaller you are, the much longer the drug will certainly be detectable. Countless of the same components are what a physician will use to determine your sheep in the very first place. Smaller people generally require reduced doses because that an equal effect contrasted to bigger individuals.


False Positives for Amphetamines

Trazodone has actually been displayed to lead to false positives on drug tests for amphetamine use. While more studies must be done on false positives in general, be sure to alert anyone administering a toxicology test around your trazodone use and also your concerns about false positives.

Labs must be conscious of what medicine can cause false-positive results. However, considering the results for failing a medicine test deserve to be quite severe in some circumstances, make doubly certain everyone is aware of potential problems connected with any kind of prescription medicine you are on is never a negative idea.

See more: When Should A Girl Start Wearing A Bra, Adolescents And Bras

While there is not lot research regarding trazodone leading to false positives ~ above a hair medicine test, the is worth stating if you have taken trazodone in the previous 90 days. Hair tests deserve to detect drug use pretty far back in your history.